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Video by Dr. Dawn Elise Snipes on integrative behavioral health approaches including counseling techniques and skills for improving mental health and reducing mental illness.
#trauma #PTSD #Glutamate

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Explore the effect of trauma on glutamate levels
Learn about the effects of glutamate on the brain
Explore symptoms of glutamate imbalance
Identify interventions to assist in recovery of the HPA-Axis, neurotransmitter balance and brain functioning

Moderate activation of the glutamatergic neurons plays an important role in synaptic plasticity (learning)
Glutamate enhances inflammation
The Goldilocks Principle: Too little glutamate excitation can result in difficulty concentrating or mental exhaustion. But too much can result in excitotoxicity, which can damage nerve cells (neurons)
Excess glutamate is thought to
Contribute to cell degeneration in Huntington’s Disease
Lead to acute movement disorders: tremor, gait disturbances, parkinsonism, dyskinesias and dystonias, myoclonus, and restless legs

Dopamine receptors located on the glutamatergic terminals
Enhance glutamate release (Licata and Pierce, 2003) in the presence of stimulants.
Dopamine further increased the excitatory neurotoxicity of glutamate

Normally, a stressor evokes a stress response involving the release of hormones to promote adaptation and is efficiently turned on and shut off. When the response is overused or dysregulated it leads to “pathophysiological processes” including stress-induced remodeling of the brain including neuronal death.
Trauma disrupts a sense of safety and can contribute to hypervigilance
Hypervigilance results in persistently elevated levels of cortisol and glutamate

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